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293,295,296 Under conditions of DNA damage, Rho-associated coiled-coil containing protein kinase 1 (ROCK1)-mediated apoptosis is increased in the MI model
PMC 8547544
Adverse events need to be evaluated by the investigator and reported to the sponsor within specified time periods (ICH E6 4.11.1,2 and E2A) Be sure to document (and report to sponsor if required) possible adverse events at study visits or as the study staff is aware
ABCB1 gene variants and antidepressant treatment outcome: a meta-analysis
[The] dorsal raphe preferentially innervates the cerebral cortex, thalamus, striatal regions (caudate-putamen and nucleus accumbens), and dopaminergic nuclei of the midbrain (eg, the substantia nigra and ventral tegmental area), while the median raphe innervates the hippocampus, septum, and other structures of the limbic forebrain
Collins J, Jones L, Snyder M, Sicard E, Griffin P, Webster L, et al
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