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In summary, a diverse array of natural products demonstrates potent immunomodulatory effects in PH models, primarily by dampening the activation of innate immune cells, including macrophages and neutrophils, restoring the balance of adaptive immunity such as the Treg/Th17 axis, and disrupting pro-inflammatory cytokine networks, specifically NF-B and NLRP3
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Their implementation requires robust computational infrastructure, interdisciplinary coordination, dynamic regulatory oversight, and enhanced training for investigators in informatics and biostatistics
Domestic manufacturers are capitalizing on India's position as the "pharmacy of the world," with contract manufacturing and private labeling services becoming significant revenue streams
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