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Gastrointestinal side effects observed under cotadutide effects are similar in quality but more severe than those under GLP-1RA treatment ( Animal data on a GLP-1/GIP/glucagon triple agonist show strong effects on body weight reduction, and glucose- and lipid normalization in rodents

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National Institute for Biological Standards and Control

Both hormones actively regulate the energy metabolism of the neurons within them

Butyrate is among the best studied SCFAs because of its impact on neurons