Its best-characterized local mechanism is upregulation of vascular endothelial growth factor (VEGF) and related angiogenic signaling, which promotes the formation of new blood vessels in damaged mucosal tissue
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Because glutamate transport into glial cells or neurons is reduced in the brains of old mice, the loss of synapses and neurons in these areas results in increased amounts of extracellular glutamate (Nickell et al., 2005
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Mitochondrial dysfunction in patients with hypotonia, epilepsy, autism, and developmental delay: HEADD syndrome