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GLP-1 Receptors Exist Throughout the Body Although GLP-1 medications work in the pancreas to regulate insulin and glucagon, GLP-1 receptors are widely distributed in other areas of the body, including the brain, cardiovascular system, immune system, gut, and kidneys, says Diana Isaacs, PharmD, CDCES, an endocrine clinical pharmacy specialist in the Endocrine and Metabolism Institute at Cleveland Clinic in Ohio
Future studies should clarify how these agents should be managed before elective arthroplasty, whether perioperative interruption affects weight or glycemic stability, and whether coordinated medication management can reduce aspiration concerns without undermining preoperative optimization
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Because Accutane is regulated through the governments iPLEDGE program, all blood test results and birth control methods must be documented and updated monthly in the system before the prescription can be issued
