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The key point is that this is the first randomized, placebo-controlled clinical evidence that a GLP-1 receptor agonist may slow the biological processes associated with aging in humans. Michael Corley, PhD Using multiple epigenetic clocks, we saw a broad pattern of slower biological aging in participants treated with semaglutide compared with placebo, including a 9% slowing in the pace of aging measured by DunedinPACE and a significant effect on PCGrimAge, which tracks processes linked to all-cause mortality and age-related disease, the researcher detailed

PlexusDx compounded semaglutide injections begin at $189/mo (or $149/mo on the 6-month plan), and your dose adjustments never change that price

When the medication is swallowed in pill form by mouth, the absorption is significantly less so the dose needs to be much higher

As such, including an additional outcome with less clinically meaningful threshold would overload the study results with redundant information rather than providing added clinical insights

(September 2004)