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A series of transporters primarily acting in the kidney is responsible for the control of UA in the blood 3 , with URAT1 (coded by SLC22A12) responsible for most kidney reabsorption into the blood and ABCG2 (or breast cancer resistance protein, BCRP) mainly involved in secretion into urine
Genotype, enzyme activity, glutathione level, and clinical phenotype in patients with glutathione synthetase deficiency
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A.RozhnovaT.KostyukS.et al
Laijawala RA
Broad-spectrum peptide inhibitors of aminoglycoside antibiotic resistance enzymes
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