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Measurements of body weight, waist circumference, and vital signs (systolic and diastolic blood pressure, and pulse) were taken at baseline and repeated every 4 weeks until week 20, followed by assessments every 8 weeks until week 100 and week 104 (within 3 days before or after the scheduled visit day)

Byetta is taken twice daily, while Bydureon is a once-weekly extended-release injection

In addition, as GLP-1 is produced, it sends a message to your brain that youre full, reducing your appetite and your cravings

Practical Application Resistance training: 2-3 sessions weekly, improves insulin sensitivity Moderate aerobic exercise: 150+ minutes weekly, reduces inflammation High-intensity intervals: 1-2 sessions weekly, enhances metabolic flexibility Daily movement: Walking, stairs, active living reduces baseline DPP-4 Post-meal walks: 10-15 minutes after eating enhances GLP-1 effects Morning exercise: May optimize DPP-4 patterns throughout the day Consistency over intensity: Regular moderate exercise beats sporadic intense sessions Strategy 5: Sleep Quality and Circadian Rhythm The Science: DPP-4 expression follows circadian rhythms

Hydration tips: Drink at least 810 glasses of water per day

Added Dr Ee: In our practice, patients do conceive successfully when they manage to lose weight effectively, regardless of whether it is through diet, exercise, medication or bariatric surgery. Dr Khoo Chin Meng, who heads the division of endocrinology at National University Hospital, also does not recommend the use of Ozempic to boost fertility