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Etiologies of DKD include environmental insults, genetic susceptibility, primarily metabolic and hemodynamic factors, etc
However, there are not many documented studies to confirm this effect
Knockdown of METTL14 by siRNA significantly reduces GPX4 mRNA m^6A modification, restores GPX4 expression, alleviates ECM degradation, and ultimately inhibits chondrocyte ferroptosis in vitro (176)
Ghule AE, Kulkarni CP, Bodhankar SL, Pandit VA
10.1016/j.cardiores.2004.12.027 10 Byrns ChinaN.PerlegosA
Carnitine is responsible for promoting the transport of fatty acids to the mitochondria, where they are "burned" (metabolized) to extract energy from them
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