Early research is mostly preclinical, so it should not be treated as a proven anti-aging or fat-loss treatment
Older adults may experience decreased absorption of B12 due to changes in the acids and enzymes required for its absorption
not primarily appetite-driven (OUP Academic) Expected weight loss (this is where many people get misled) In major obesity trials: Semaglutide 2.4 mg weekly: ~14.9% mean weight loss at 68 weeks (STEP-1) (PubMed) Tirzepatide: ~15.0% to ~20.9% mean weight loss at 72 weeks , dose-dependent (SURMOUNT-1) (PubMed) AOD-9604s best-known human signal is kilograms, not double-digit percentages , and later studies did not sustain a strong obesity-drug profile
They are not intended for human consumption, medical, diagnostic, or therapeutic applications
GLP-1 receptor agonists and gallbladder disease risk
It is not a drug, food, or cosmetic, and must not be misrepresented, misused, or mislabeled as such.