A spokesperson for Eli Lilly, which produces Zepbound and Mounjaro, told The Independent that Zepbound and Mounjaro autoinjectors and Zepbound vials are approved for single-use onlydose-splitting or microdosing is not contemplated by the FDA-label and may pose patient safety risks. Novo Nordisk, which produces Ozempic and Wegovy, told The Independent the company "[does] not condone the misuse of our products." The company noted it is concerned about non-FDA approved knock-off versions of semaglutide and sources spreading misinformation about GLP-1s to the public. The FDA warns that using unapproved versions of GLP-1 drugs can be risky for patients. This story was updated on September 4, 2025 to include responses from Eli Lilly and Novo Nordisk Join our commenting forum Join thought-provoking conversations, follow other Independent readers and see their replies Comments
Glucose-dependent insulinotropic polypeptide receptor therapies for the treatment of obesity, do agonists=antagonists
The bigger benefits, like better insulin sensitivity, slower digestion, and less body fat, show up closer to 6 to 8 weeks
Table 2 Recommended daily intake for each B complex vitamin and the associated neurological and psychiatric manifestations resulting from their deficiencies
PMC 1559654
However, the drugs also appeared to lower blood pressure independently of weight loss