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Figure 1 4.1 Macrophage fatty acid metabolic disorders potentiate MSU crystal-induced inflammation Numerous studies have shown that the inflammatory factor interleukin-1 beta (IL-1) is essential for MSU crystal-driven inflammation and is released, in place of infiltrating neutrophils or monocytes, from the resident macrophages in the initial stage of GA (38, 39)
The evidence for DSIPs effectiveness in chronic insomnia is still inconclusive
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