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First, researchers should assess whether their primary hypothesis involves isolated collagen induction or comprehensive tissue remodeling this single question typically resolves the Matrixyl vs GHK-Cu selection in most study designs

The week-by-week progression shows this pattern clearly

In families of patients with PA (pernicious anaemia), ulcerative colitis, rheumatoid arthritis, polymyalgia, psoriasis, sarcoidosis, lupus were in one study more common than in those of people without PA

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Data availability The datasets analyzed during the current study are not publicly available but are available from the corresponding author upon reasonable request