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Early data suggest that engaging all three receptors may produce a more pronounced reduction in body weight than single or dual agonists, though no head-to-head outcome trials have yet been completed
It doesn't just patch the problem
Importantly, GLP-1 receptor agonists are not indicated for type 1 diabetes or diabetic ketoacidosis, and should not be co-prescribed with DPP-4 inhibitors (such as sitagliptin or linagliptin)
TAC, transverse aortic constriction
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use is recommended only if the potential benefit justifies the potential risk
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