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Preclinical studies suggest that GLP-1 signaling in the central nervous system may influence neuronal activity patterns, though the clinical significance of these findings for human fatigue remains theoretical

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Here we focus on FAO occurring in the mitochondria (Fig

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Core molecular mechanisms encompass the targeted modification of inflammatory signaling molecules [408], oxidative alteration of pathogen entry-related proteins [204], and direct damage to host lipids/DNA [409]

They're saying look, 'I'm not really thinking down the road about whether I'm gonna be on these meds in a year or not