Given the role of carnitine transporters in cancer metabolism, targeting these transporters could disrupt FAO and potentially inhibit tumor growth.Carnitine transporters can be exploited for targeted drug delivery, enhancing the efficacy of chemotherapy.Expression levels of carnitine transporters like OCTN2 and CT2 could serve as prognostic markers for certain cancers
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NAMPT regulates PKM2 nuclear location through 14-3-3zeta: Conferring resistance to tamoxifen in breast cancer
Early autophagy inhibits cancer progression, but with the continuous growth of tumors, autophagy provides nutrients and energy for tumor survival (46)
When fetal fibroblasts were treated with Epitalon over multiple passages, they were able to bypass the Hayflick limit, dividing beyond 44 passages, compared to just 34 in untreated controls [26]
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