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The long-acting strategies of GLP-1 drugs (amino acid substitutions, fatty acid side chain modifications, Fc fusion proteins, PEGylation) described in the article are only a small part of the current long-acting strategies, which have actually been applied to other protein-peptide drugs as early as
Uncommon side effects of Wegovy include: fast heartbeat an increase in pancreatic enzymes, which will show up in blood tests delayed emptying of the stomach (gastroparesis) hypoglycemia in people without diabetes an increased level of bilirubin in the blood, which can cause jaundice symptoms include yellowing of the whites in your eyes and skin Wegovy also has some serious side effects, which should be treated straight away : In diabetic patients, a common serious side effect is complications of diabetic eye disease (diabetic retinopathy)
GLP-1 medications produce lasting results only when combined with sustainable lifestyle changes
Individuals with medical conditions: Those with gastrointestinal issues like Crohns disease or celiac disease or individuals who have undergone bariatric surgery often struggle with absorption
doi: 10.1007/s00125-010-1955-x
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