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J Med Chem (2007) 50:612632

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Tumor necrosis factor- elevates neurite outgrowth through an NF-B-dependent pathway in cultured adult sensory neurons: Diminished expression in diabetes may contribute to sensory neuropathy

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GLP-1, secreted by the intestine, brainstem, and pancreas, also exerts appetite-suppressing and gastric emptying-delaying effects on the hypothalamus