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Cell Mol Immunol 21 , 103118 (2024)

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Furthermore, participants assigned to tirzepatide had a slower mean rate of decline in estimated glomerular filtration rate over the study period: 1.4 0.2 ml/min/1.73 m 2 body mass per year with tirzepatide compared with 3.6 0.2 ml/min/1.73 m 2 body mass per year with insulin glargine, for a between-group difference of 2.2 ml/min/1.73 m 2 body mass per year [95% CI 1.62.8 ml/min/1.73 m 2 body mass per year] [95]

Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health under award numbers R41CA240124, R42CA240124, R37CA065910, and P30CA023074

Lysozyme from chicken egg white (Sigma) was dissolved in phosphate-buffered saline 1, pH 7.4 (PBSRoth) at 5 mg/ml