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In their 2023 paper, Ingrassia et al
Excretion Mainly excreted through urine and bile, with a half-life of approximately 6 to 8 hours
Effectively delivered means what actually reaches your bloodstream
Gentle yet effective
Neurosci Biobehav Rev 114:134155 Zhang L, Huang J, Zhang Z, Cao Z (2021) Altered metabolites in the occipital lobe in migraine without aura during the attack and the interictal period
It is important not to self-treat with high-dose B12 supplements before seeing your GP if you suspect deficiency, as this can interfere with diagnostic blood tests and potentially mask underlying conditions such as pernicious anaemia
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