Brain microvascular endothelial cells express five carriers for the amino acid alanine belonging to two groups, neutral amino acid transporters (ASCT/SLC1A) or small neutral amino acid transporters (SNAT/SLC38A)
doi:10.4061/2011/716871, PMID: 21461368 Hsu M, Srinivas B, Kumar J, Subramanian R, Andersen J (2005) Glutathione depletion resulting in selective mitochondrial complex I inhibition in dopaminergic cells is via an NO-mediated pathway not involving peroxynitrite: implications for Parkinsons disease
PMID: 70 WangYTianQHaoYYaoWLuJChenCet al
Sources NIH/PMC Randomized controlled trial of oral glutathione supplementation on body stores of glutathione NCBI Randomized clinical trial: long-term GSH supplementation in elderly type 2 diabetes Frontiers in Nutrition Glutathione: protection against oxidative stress, aging, and inflammation PMC Safety and efficacy of glutathione supplementation for skin lightening: narrative review Wiley Glutathione homeostasis and functions: potential targets for medical interventions Drugs.com What is glutathione used for
Supernatants were quantified and analysed by western blotting
The DNA regulatory sequence accountable for stimulation by indirect antioxidant pathway inducers was identified as an antioxidant response element (ARE), while Nrf2 was subsequently recognized as the xenobiotic-activated receptor (XAR) major regulator responsible for the activation of ARE-dependent drug metabolizing enzymes [39]
