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Furthermore, these molecules also have extrapancreatic mechanisms of action that contribute to their glucose lowering properties, such as slow gastric emptying and increase satiety (Figure 1)

It is important to note that these clinical trials were designed as non-inferiority studies

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Best consumed in the morning for optimal absorption

But the absorption profile, how quickly the medication reaches peak levels and how gradually it tapers, does shift slightly depending on where you inject

All of these studies are hypothesis-generating and await confirmation in RCTs. According to Lane, the rationale for GLP-1 receptor agonists in lupus stems from the drugs demonstrating anti-inflammatory properties, potentially by inhibiting the NF-B pathway, which plays a crucial role in inflammation