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The pharmaceutical formulation disclosed herein may be used in: (i) the prevention and/or treatment of any form of diabetes and associated symptoms, such as hyperglycaemia, type 2 diabetes, impaired glucose tolerance, type 1 diabetes, non-insulin dependent diabetes, maturity onset diabetes of the young (MODY), gestational diabetes and/or for the reduction of HbA1c
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The medication follows a specific titration schedule designed to minimize gastrointestinal side effects while gradually increasing therapeutic effect
Rather than focusing on single factors in isolation, modern approaches calculate overall risk by combining multiple variables
Based on further evidence found in HEK cells, it appears that a mechanism that depends on Gq might trigger the activation of protein kinase C (PKC) and ERK 1/2
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