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Are there other treatment options

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Introduction Traditionally, vitamin B 12 replacement is administered intramuscularly (IM)

On the other hand, chronic kidney disease causes fast excretion of cobalamin through urine, resulting in low levels

Methionine in turn is required for the synthesis of S-adenosylmethionine, a methyl group donor used in many biological methylation reactions, including the methylation of a number of sites within DNA, RNA, and proteins ( Figure 1 ) (3)

Structural studies of retatrutide bound to GLP-1R, GIPR, and GCGR have been deposited in the Protein Data Bank, supporting docking, mutagenesis, and structure-activity work in computational pharmacology