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3 Due to their clinical appearance, labial melanotic macules can sometimes be difficult to differentiate from venous lakes or oral melanoma

Very large meals A too-big meal can pile on fullness and pressure, and it can worsen reflux for some people

Recent evidence remains mixed: a meta-analysis of randomized trials reported a slight increase in pancreatitis risk among GLP-1 RA users, whereas a large real-world analysis found no excess risk in a comorbidity-free population [29, 30]

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Last Published 09.01.2025 Effective Date: 09.01.2025 This policy addresses the use of Vyepti (Eptinezumab) for the treatment of chronic and episodic migraine