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The cryo-EM structures of retatrutide-bound GLP-1R, GIPR and GCGR reveal a combination of conserved peptidereceptor interactions and receptor-specific conformations, particularly in ECL1, that enables retatrutide to execute agonism at multiple receptors
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Design of mesoporous silica nanoparticles for the treatment of amyotrophic lateral sclerosis (ALS) with a therapeutic cocktail based on leptin and pioglitazone
doi:10.1111/dom.13339 8
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