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16:00 Comparing Novos Triple to Retatrutide Analysis of weight loss percentages versus Lillys retatrutide data and the caution required when comparing across trials
Libido: moving in both directions 35% reported no change 29% reported higher libido 19% reported lower libido Body confidence and sex life 70% of women reported improvements in body confidence and sex life Mood and lifestyle changes 45% said their mood became more stable 53% lost interest in foods they previously enjoyed 49% reported reduced desire to drink alcohol What this tells us GLP-1 may influence behavior, emotional state, habits
One of the ongoing debates about this entire class of medications is whether the effects are mediated solely by weight loss and mitigation of the inflammatory consequences of energy toxicity (read: too many calories) versus other biological effects of these medications
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Peppermint tea is another option that some find soothing
SLC7A7 is a cationic amino acid transporter which is abnormally upregulated in the kidney tissue of DKD and shows a positive correlation with the ferroptosis driver ACSL4 and fibrosis markers, including -smooth muscle actin (-SMA) and collagen type Ia 1 ( Col1a1 ) (Zhao et al., 2025a)
