Dulaglutide inhibits the expression of PAI-1 by restoring the expression of SIRT1 and eNOS, restores telomerase activity and finally alleviates high glucose-induced oxidative stress in HRECs [122]
Conflict of interest Author RS and XL were employed by the company Guangdong Xingwa Agricultural Technology Co., Ltd
The Journal of investigative dermatology, 113(3), 364368
PubMed laboratory research record [PMID: 6463365] PubMed record related to this compound for laboratory literature review
By reducing glucagon secretion when glucose levels are elevated, GLP-1 agonists help decrease hepatic glucose output, further improving overall glucose homeostasis
These reactive oxygen species such as free radicals, hydrogen peroxide (H2O2) and lipid peroxides can damage our mitochondria and limit ATP production (our main energy molecule)