For patients seeking visible skin improvement, injectable glutathione remains the preferred choice
Maintenance phase: After noticeable improvement, some protocols suggest reducing to 2-6 mg per month , adjusted according to clinical evaluation
Concurrently, AGEs further blunt insulin-receptor signaling via the AGEs/RAGE pathway, reducing receptor autophosphorylation and downstream transduction [340]
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For biochemical assays, total liver lipids were extracted using chloroform/methanol (21, v/v)