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Long-Term Impact of Vitamin A Deficiency Even marginal or subclinical vitamin A deficiency during pregnancy or infancy can result in long-term impairments in cognition, emotion regulation, sensory processing, and behaviordomains heavily affected in ASD [9]

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Abstract Inability to achieve therapeutic concentrations of a medication in the brain due to the blood brain barrier (BBB) is the major cause of treatment failure for most brain diseases

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BioMed Research International, 2012, 153626