The treatment given to this patient resulted in an improved microbiome with an increase in bacterial diversity, partly due to an increase in the relative abundance of butyrate-producing bacterial species, which were paralleled by an increase in butyrate concentration, an anti-inflammatory SCFA (Engen et al., 2020)
These include patients with personal or family history of medullary thyroid cancer, MEN2 syndrome, severe kidney disease, acute pancreatitis, or diabetic retinopathy
Provider supervision matters because a safe plan should include health-history review, medication review, lab evaluation when appropriate, nutrition support, hydration guidance, side-effect monitoring, and follow-up care
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This combined approach is often discussed for people who need additional appetite control beyond GLP1 therapy alone
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