Additionally, E2 is known to be able to signal through the insulin-like growth factor 1 receptor (IGF-1R) in the skin in a non-genomic manner and this process has been implicated in the regulation of cutaneous aging (Emmerson and Hardman, 2012)
Ruze R, Liu T, Zou X, Song J, Chen Y, Xu R, Yin X, Xu Q (2023) Obesity and type 2 diabetes mellitus: connections in epidemiology, pathogenesis, and treatments
Development of New Formulations : Scientists are exploring new formulations of GLP-1 agonists to optimize their delivery and improve patient adherence to treatment regimens
Biomolecules & Therapeutics, 24 (6), 630-637
36 Dapagliflozin EMA product information (2023)
1.3 Overview of GLP-1's physiological roles GLP-1 demonstrates various physiological impacts across several systems in the body, as shown in Table 1