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Additional experiments showed that increasing GSH levels using glutathione diethyl ester worsened diabetes, whereas blocking GSH synthesis with L-buthionine sulfoximine improved glucose tolerance, further highlighting the importance of GSH metabolism in disease progression

Debunking the myth: Broader application: While GLP-1 agonists were originally developed for the treatment of type 2 diabetes, their benefits extend beyond blood sugar control

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10.1111/obr.13725 40 YunJ.-S.KoS.-H