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Here, we show that in mouse islets, tirzepatide stimulates insulin secretion predominantly through the GLP-1R, owing to reduced potency at the mouse GIPR
Published: 09-Dec-2024, DOI: 10.35248/0975-0851.24.16.606 Background: The human GLP-1 receptor agonist, semaglutide, functions by binding to albumin, which is facilitated by modifying position 26 lysine with a hydrophilic spacer and a C18 fatty di-acid
These factors highlight the need for careful consideration and monitoring when prescribing these medications, especially in individuals at risk of eating disorders (Bartel et al., 2024)
Also mentioned in this episode are Duly Health and Care
The molecule may be interesting, but the vial from a research supplier in an unregulated jurisdiction is a different question entirely
That is a conversation to have with your GP or a specialist haematologist, not a reason to add a private injection on top of an NHS schedule without telling either provider
