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Less than 5% body weight loss after 16 or more weeks at a therapeutic dose (10mg or above) constitutes a poor response
However, it is important to note that retatrutide remains an investigational drug it has not yet received regulatory approval from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA) for routine clinical use in the UK
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At lower doses, the GLP-1 provides support
However, turmeric-based supplements have been increasingly implicated in drug-induced liver injury and thus, should be used with caution in patients with underlying liver disease
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