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This suggests that the GLP1/GIP pathway can increase efficacy over GLP-1RAs [99]

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Secondly, we implemented several design features to mitigate biases: we defined a causal framework, used direct acyclic graphs to guide the selection of confounders, specified new user, active comparator target trials, and used inverse probability weighting to adjust for a comprehensive set of covariates from multiple data domains

However, genetic predisposition does not predict exact medication response and should always be interpreted with a qualified healthcare provider