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This paper reviews the most relevant experimental studies that have contributed to a better understanding of the molecular mechanisms and intracellular pathways involved in cardioprotection induced by GLP-1 and analyzes in depth its potential role as a therapeutic target both in the ischemic and reperfused myocardium and in other conditions that are associated with myocardial remodeling and heart failure

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The study design was adapted following consultation with participants and care partners, to facilitate trial participation and improve participants experience during the trial

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Proper injection technique includes maintaining 2.55 cm distance between consecutive injections and avoiding scars, moles, or areas with skin abnormalities