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Monitor renal function in patients who develop significant gastrointestinal symptoms According to NICE guidance (NG28), GLP-1 receptor agonists like Ozempic should only be continued if there is a beneficial metabolic response, defined as a reduction in HbA1c of at least 11 mmol/mol (1.0%) and weight loss of at least 3% of initial body weight at 6 months

A 2023 study in JAMA found that people using GLP-1 drugs like Ozempic were much more likely to develop gastroparesis than those not taking these medications

Semaglutide is injected subcutaneously (under the skin)

To help prevent these issues, Wegovy is started at a low dose and titrated gradually