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While essential for preserving the drugs potency, these components can occasionally irritate the surrounding tissue, especially in individuals with more sensitive skin

Animal studies show mostly mild local irritation at injection sites

Efficacy and safety of tirzepatide versus placebo in overweight or obese adults without diabetes: A systematic review and meta-analysis of randomized controlled trials

These medications work on overlapping pathways and should not be combined

Factors such as medication dose, adherence, initial weight, and presence of diabetes can all influence your outcome

People should always confirm which drugs have FDA approval for weight loss before starting them