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In the short-term, demand may be somewhat curbed by governments and insurers being slow to reimburse, high out-of-pocket costs, supply shortages and side effect fears

However, injection site reactions can be a problem for some people using GLP-1 agonists

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[4] In case of accidental large overdose (e.g., someone receives far more frequent injections than prescribed), monitoring for symptoms like flushing, tingling in extremities, or liver enzyme elevations would be prudent

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