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This catecholamine surge increases alertness, suppresses appetite through stimulation of the hypothalamus, and elevates heart rate and blood pressure as secondary effects

Many GLP-1 users become less active as their appetite and food-reward drive is suppressed

JAMA 2024, 331, 654664

10.1210/jc.2001-011441 152

We saw skyrocketing utilization of GLP-1s, and we saw a few reports investigating one outcome or another, Ziyad Al-Aly, MD, clinical epidemiologist, Washington University in St