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NICE NG246 (2025) recommends lower BMI thresholds (27.5 instead of 30, and 24.5 instead of 27) for South Asian, Chinese, Other Asian, Middle Eastern, Black African, and African-Caribbean backgrounds, because type 2 diabetes risk rises at lower BMIs in these populations 3,5

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Important contraception consideration: Tirzepatide delays gastric emptying and can reduce the absorption of oral contraceptives

Frequently asked questions When used correctly and alongside healthy lifestyle changes, weight loss injections can be an effective part of a long-term plan

A streamlined approach aligns labs with decision points, such as dose escalation or annual risk assessment