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Tirzepatide, on the other hand, is a glucose-dependent insulinotropic polypeptide (GIP) receptor and GLP-1 receptor agonistsometimes called a dual GIP/GLP-1 receptor agonist

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The conversion guidance that exists for transitioning between other GLP-1 agonists can provide some framework for thinking about dosing during transitions, though no specific tirzepatide-to-retatrutide conversion protocol has been established in clinical literature

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