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Description

TGR was also identified as a multifunctional oxidoreductase with a remarkably wide substrate specificity, capable of directly reducing peroxides, selenium-containing compounds, and several important low-molecular-weight antioxidants, as well as Trx, DTNB, GSSG, and GSH-HED

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Board P (2011)

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Over time, this leads to chronic disease, autoimmunity, and cancer

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Based on these observations, ebselen was concluded to be the GPx mimic

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