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Signs of Degradation Don't use the reconstituted solution if it appears cloudy, contains visible particles that don't dissolve with gentle swirling, or has changed color
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Its a slightly newer medication, however, and it can do a better job at targeting PDE-5 without collaterally affecting PDEs 6 and 11, inhibition of which is the source of some sildenafil side effects.31 As such, vardenafil is a good choice for men who've tried sildenafil and noticed certain side effects like muscle pain or changes in vision
