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12 (7), e2410107

Binding properties of ferrocene-glutathione conjugates as inhibitors and sensors for glutathione S-transferases

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Given the association of GSSG with the oxidative protein folding environment in the ER, we examined whether etomoxir could make the ER more oxidizing to proteins in the lumen

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To further corroborate this observation, we inactivated the ADH5 gene in the non-blood derived human colorectal carcinoma cell line HCT116 by CRISPR/Cas9 (Supplementary Fig