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The Scale of the Pipeline The breadth of development activity reflects the commercial and clinical ambitions of a drug class that has arguably become the most consequential in modern medicine

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For example, studies involving GLP-1 RAs have been shown to reduce major adverse cardiovascular events in patients with T2DM

Positive results in animal studies dont always translate to results in humans

Key Takeaway: Current human evidence suggests that for the vast majority of people, GLP-1 medications do not cause thyroid cancer

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