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The migrating motor complexes in patients whose disease has a neuropathic etiology have a normal amplitude, but they are ill-coordinated and cannot propagate

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Excessive ROS can oxidatively modify KEAP1, leading to its separation from NRF2, activating the expression of antioxidant genes

Additionally, K-Ras-driven cells are characterized by increased expression of GOT1 and GOT2 182,183

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