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Further evidence of hemodynamic benefit is suggested by a recent mediation analysis from EMPA-REG showing that markers of plasma volume such as hematocrit and hemoglobin were important markers associated with reduction in cardiovascular mortality observed with SGLT2i use (10,78)

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Obes Surg 35(3):11271134 Esparham A et al (2024) Safety and efficacy of glucagon-like peptide-1 (GLP-1) receptor agonists in patients with weight regain or insufficient weight loss after metabolic bariatric surgery: a systematic review and meta-analysis

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