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Retesting B12 blood serum levels to verify they are increasing as expected

Commonly used brand name(s) In the U.S

But they can be (and often are) prescribed off-label for that purpose, which is why theyre included in the table below

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The final predicted expression of both CBS OPT and L2HGDH OPT were MYPYDVPDYALQISCBS OPT (or L2HGDH OPT )DYKDDDDKKSRGPGRATGAAANSAVDGTAGPGSTGSRVDGSGEGRGSLLTCGDVEENPGP (with the features: HA tag, amino acid linker 1, CBS OPT (or L2HGDH OPT ), FLAG, amino acid linker 2, T2A self-cleavage site, in the order of N to C terminal) (#230088 and #230089, Addgene)

Early clinical trial participants reported visible improvements within 2 weeks of use